Laboratory Technician: Therapeutic Discovery in

vor 7 Monaten

Wien, Österreich CeMM Vollzeit

We are looking for a highly motivated laboratory technician who is excited to work within an international consortium on the identification and development of novel therapeutic strategies for the treatment of childhood cancers.

**Profile**:
Typical tasks

Tasks and responsibilities contain, but are not limited to:

- Cell Culture (maintenance, manipulation via genome engineering)
- High throughput drug screens using our automated facility
- Functional genomics including CRISPR/Cas9 screens and protein stability reporter screens
- General molecular biology techniques (immunoblots, cloning, immunoprecipitations)
- Technology development
- Training of new lab members
- Certain lab management responsibilities

The Winter Lab

We are an international and multi-disciplinary research lab. When you work with us, you will work in a team of molecular biologists, biochemists, and medicinal chemists. Through our international consortium, we also have access to medical doctors, clinical trial specialists and patient advocates. Our mission is to connect that wide umbrella of backgrounds to reimagine the treatment of solid tumors in children by finding drugs that induce the degradation of well-known drivers of these diseases. You’d be working with high-throughput technologies such as genome-wide CRISPR/Cas9 screens, phenotypic drug screen and proteomics. The setup in our group and in our consortium is interdisciplinary, diverse, and inclusive. This fosters an environment that is required for the generation of innovate ideas and novel concepts that are needed to advance novel therapeutic strategies.

The Principal Investigator

Georg Winter obtained his PhD from the Medical University of Vienna, working on elucidating the mechanism of action of anti-neoplastic drugs under the supervision of Professor Giulio Superti-Furga at CeMM. He specialized in proteomics as well as chemical genetic approaches to identifying drug resistance mechanisms and on mechanistically elucidating synergistic drug combinations. He continued his training in chemical biology, working as a postdoctoral fellow with Dr. James Bradner at the Dana Farber Cancer Institute/Harvard Medical School. There, he innovated a generalizable pharmacological solution to in vivo target protein degradation and applied this strategy to the study of leukemic gene regulation. Georg Winter was recruited as CeMM principal investigator in June 2016. His lab develops and applies methods for target protein degradation with the ultimate goal of understanding and disrupting oncogenic transcriptional circuits. To that end, the Winter laboratory combines phenotypic drug screens, chemical genetics, and drug-target identification approaches with holistic measurements of global gene activity and genome structure. The ultimate goal of the research conducted in the Winter laboratory is to connect basic research in gene regulation and the ubiquitin proteasome system with functional genomics and chemical probe development to develop novel and personalized therapeutic paradigms.

About the Institute

We offer
- Work within an experienced, interdisciplinary, and international team at one of Austria’s leading research institutes
- Ample opportunities to contribute and gain experience in a key area of biomedical research and precision medicine
- An inspiring workplace with an international setting, strong team spirit, and an excellent work climate
- A wide range of social, cultural, and sports activities organized by the institute
- Excellent employee benefits including full insurance coverage (health, accident, retirement), health care services, subsidized cafeteria
- Minimum monthly gross salary of EUR 2.850,00 paid out 14 times yearly (following the recommendations of FWF).
- Support for relocating to Vienna is provided (relocation reimbursement, visa support, etc.)

  • In Vivo Research Laboratory Scientist

    vor 2 Wochen

    Wien, Österreich Boehringer Ingelheim Vollzeit

    **In vivo Research Laboratory Scientist (Lab Technician) - In Vivo Cancer Pharmacology (f/m/d)** **-** **233862** **THE POSITION** We are currently seeking in vivo Research Laboratory Scientists to join the Cancer Pharmacology and Disease Positioning Department. The positions will strengthen our multi-disciplinary research team focused on discovering and...

  • Laboratory Technician in Proteomics

    vor 4 Monaten

    Wien, Österreich CeMM Vollzeit

    The mission of CeMM, the Research Center for Molecular Medicine of the Austrian Academy of Sciences, is to achieve maximum scientific innovation in molecular medicine for the improvement of health care. CeMM is an international research institute and a founding member of EU-LIFE, an alliance of leading European life science institutes. At CeMM, an...

  • Research Laboratory Scientist

    vor 2 Wochen

    Wien, Österreich Boehringer Ingelheim Vollzeit

    Research Laboratory Scientist - In Vivo Cancer Pharmacology (f/m/d)-2213256 **THE POSITION** As of now we are seeking in vivo Research Laboratory Scientists to join the Cancer Pharmacology and Disease Positioning Department. The positions will strengthen our multi-disciplinary research team focused on discovering and characterizing innovative drugs for...

  • Research Laboratory Scientist

    Vor 7 Tagen

    Wien, Österreich Boehringer Ingelheim Vollzeit

    Research Laboratory Scientist - In Vivo Cancer Pharmacology (f/m/d)-228767 **THE POSITION** As of now we are seeking in vivo Research Laboratory Scientists to join the Cancer Pharmacology and Disease Positioning Department. The positions will strengthen our multi-disciplinary research team focused on discovering and characterizing innovative drugs for...

  • Laboratory Technician in Metabolomics

    vor 7 Monaten

    Wien, Österreich CeMM Vollzeit

    CeMM, the Research Center for Molecular Medicine of the Austrian Academy of Sciences is an international, independent and interdisciplinary research institution located at the Campus of the Vienna General Hospital and Medical University of Vienna. The Molecular Discovery Platform at CeMM is looking for a Laboratory Technician in Metabolomics (M/F/d) Your...

  • Hydrology Laboratory Technician(G4)

    vor 4 Monaten

    Wien, Österreich International Atomic Energy Agency Vollzeit

    Hydrology Laboratory Technician(G4) - (2024/0493 (006022)) Organization: NAPC-Isotope Hydrology Laboratory Primary Location: Austria-Vienna-Vienna-IAEA Headquarters Job Posting: 2024-09-12, 7:22:04 AM Closing Date: 2024-10-03, 4:59:00 PM Duration in Months: 36 Contract Type: Fixed Term - Regular Probation Period: 1 Year Full Competitive Recruitment:...

  • Discovery Scientist in Immunology

    vor 1 Woche

    Wien, Österreich Solgate GmbH Vollzeit

    Discovery Scientist in Immunology (Postdoc level) Solgate is a new research-driven biopharmaceutical startup that develops drugs targeting solute carrier (SLC) proteins, the largest family of membrane transporters. By modulating the function of the “gates” to cellular metabolism, Solgate aims to address unmet medical needs in neurological diseases, in...

  • Laboratory Automation Technician

    vor 2 Wochen

    Wien, Österreich Ribbon Biolabs Vollzeit

    Ribbon Biolabs is an early-stage biotech start-up company with locations in Vienna, Austria and in Klosterneuburg (outskirts of Vienna) developing the next technological wave of error-proof DNA synthesis. With our approach, we are developing a cost-efficient platform to produce long and complex DNA molecules, thereby enabling a new generation of...

  • Laboratory Scientist

    vor 22 Stunden

    Wien, Österreich BOEHRINGER Ingelheim RCV GmbH & Co KG Vollzeit

    **The position**: This is a two year fixed term contract with an option for extension. **Tasks & responsibilities**: - Characterization of biomarkers for novel therapeutic approaches, supporting the development of novel cancer drugs with molecular and cellular biology expertise - Independent planning, coordination, implementation and documentation of NGS...

  • Therapeutic Strategy Manager

    vor 9 Monaten

    Wien, Österreich Novotech Asia Vollzeit

    **Reporting to**: As indicated on current organisation chart. **Minimum Qualifications & Experience**: Graduate in a clinical or life sciences related field. Relevant experience/qualifications in allied professions may also be considered. Must be able to communicate clearly, able to prioritise, meet deadlines and able to work well in teams across...

  • Laboratory Automation Technician

    vor 7 Monaten

    Wien, Österreich Ribbon Biolabs Vollzeit

    Ribbon Biolabs is a biotech company headquartered in the vibrant city of Vienna. We are developing the next technological wave of error-proof DNA synthesis. With our approach, we are introducing a cost-efficient platform to produce long and complex DNA molecules, thereby enabling a new generation of biopharmaceutical processes and other synthetic biology...

  • Laboratory Support Technician

    vor 1 Woche

    Wien, Österreich IST Austria Vollzeit

    Full Time (40h/w) Klosterneuburg (Vienna), Austria € 32,100* gross/year Your Responsibilities The Lab Support Facility (LSF) of IST Austria supports experimental scientists by providing necessary laboratory infrastructure and technical support, laboratory safety, laboratory cleaning and waste disposal as well as common resources like cell culture...

  • Dairy Laboratory Technician

    vor 3 Wochen

    Wien . Bezirk (Innere Stadt), Österreich Würzburger Milchwerke GmbH Vollzeit

    **Über uns**">Die Würzburger Milchwerke GmbH ist ein Unternehmen der Lactalis Gruppe und wurde 2022 gegründet. Wir bieten innovative Lösungen für die Milchwirtschaft und sind auf dem Weg, um den Markt zu erobern.">**Gehalt**">Das Gehalt für unseren Milchwirtschaftlichen Laboranten liegt bei etwa 42.000 bis 50.000 Euro pro Jahr, abhängig von Erfahrung...

  • Laboratory Animal Care Technician

    Vor 2 Tagen

    Wien, Österreich Boehringer Ingelheim Vollzeit

    **Laboratory Animal Care Technician / Labortierpfleger (w/m/d)** **-** **231751** **DIE STELLE** Wir suchen Unterstützung für unser multidisziplinäres Team im Bereich in vivo Pharmakologie eingebettet in unsere, auf Entwicklung innovativer Wirkstoffe zur Behandlung von Krebs-Erkrankungen spezialisierte, Arzneimittelforschung. Als Teil eines engagierten...

  • (Senior) Lab Technician

    vor 1 Woche

    Wien, Österreich HOOKIPA Biotech GmbH Vollzeit

    **Position Summary**: **Main Responsibilities**: - Cell culture of human and murine cell lines and primary cells - Perform _in vitro _and _ex vivo_ immunological assays - Contribute to _in vivo_ studies such as tumor growth monitoring - Lead optimization and set-up of novel experimental approaches - Independent planning, analysis, interpretation, and...

  • Laboratory Scientist in The Ngs Laboratory of

    vor 2 Wochen

    Wien, Österreich Boehringer Ingelheim Vollzeit

    Laboratory Scientist in the NGS laboratory of Translational Medicine and Clinical Pharmacology (f/m/d)-2213140 **THE POSITION** This is a fixed term contract for 3 years with option for extension. **Tasks & responsibilities** - Characterization of biomarkers for novel therapeutic approaches, supporting the development of novel cancer drugs with molecular...

  • Research Laboratory Scientist

    vor 7 Monaten

    Wien, Österreich Boehringer Ingelheim Vollzeit

    **Research Laboratory Scientist - Analytics (f/m/d) - Limited Contract for 1,5 years** **-** **236251** **THE POSITION** We are looking for a Laboratory Scientist in our small molecule Analytics Laboratory, to support our oncology drug discovery efforts in the Department of Drug Discovery Sciences at Boehringer Ingelheim RCV & Co KG. You will join our...

  • Research Laboratory Scientist: Cancer Immunology

    vor 1 Woche

    Wien, Österreich Boehringer Ingelheim Vollzeit

    **Research Laboratory Scientist: Cancer Immunology Research (f/m/d) - Fixed term contract until 31.12.2027** **-** **233924** **THE POSITION** We are seeking a highly motivated and creative Research Laboratory Scientist with a passion for bioinformatics, genomics and big data to join a hybrid wet/dry-lab group in our Cancer Immunology team in Vienna. The...

  • Senior Therapeutic Specialist

    vor 4 Monaten

    Wien, Österreich Gilead Sciences Vollzeit

    For Current Gilead Employees and Contractors: Please log onto your Internal Career Site At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer - working relentlessly to develop therapies that help improve lives and to ensure access to these therapies...

  • Laboratory Technician

    vor 21 Stunden

    Wien, Österreich Austrian Institute of Technology Vollzeit

    We are Austria’s largest research and technology organisation and an international player in applied research for innovative infrastructure solutions. This makes us a powerful development partner for industry and a top employer in the scientific community. Our **Center for Health & Bioresources** is seeking to hire new Ingenious Partners for our location...