Principal Scientist Preclinical PK/PD Modelling Cancer Research
vor 1 Monat
We are seeking a highly skilled Principal Scientist to join our Vienna Discovery Research Team for cancer research. As a key member of our team, you will be responsible for shaping decisions regarding drug development, modes of action, and dosage regimens to achieve the desired therapeutic effect for cancer patients.
Key Responsibilities:- Represent PK/PD modelling in discovery research project teams in the realm of pharmacological cancer research at Boehringer Ingelheim.
- Perform high-quality PK/PD modelling and simulation analyses to support research projects by contributing to informative study designs of preclinical PK and/or PD experiments, by performing high-quality human PK and dose predictions, and by contributing to strategies to better understand the PK/PD relations of our candidate drugs.
- Identify modelling opportunities together with Boehringer's cancer research project teams in Austria, Germany, and the US.
- Interwork with Boehringer's research lab heads, (preclinical) modelling scientists across therapeutic areas, experimental lab scientists, and translational medicine researchers for model establishment, model parametrization, model training, and model interpretation to transform modelling into actionable hypotheses for research project teams.
- Be an advocate for PK/PD-informed decision making, also to understand implications of signal transduction and pharmacometric analyses within cancer research (researchers, project teams, management).
- As Principal Scientist, you will coach and support the development of (junior) research scientists across therapeutic areas.
- As Principal Scientist and depending on your experience, you might additionally represent and coordinate Research DMPK disciplines in international Research Project Teams. This includes establishing and maintaining external collaborations and supporting licensing activities.
- PhD in PK/PD modelling or any related scientific field (such as applied mathematics, systems biology, computational biology,...) with practical experience in ODE-based modelling. Experienced professionals with a master's degree in above area and significant practical experience in PK/PD Modelling are also considered.
- Solid skills in one relevant programming language (R, Python, MATLAB) are a must.
- Industry experience, experience in the preclinical PKPD field, or experience in oncology are considered beneficial but not mandatory.
- Excellent English communication skills are required.
- Experience in working in and leading matrix-style project teams is considered beneficial.
- Flexible working time models/home office depending on the position.
- Additional off-days (bridge-days) for more leisure time.
- Staff restaurant with a variety of lunch options for your daily well-being.
- Position-specific training opportunities for your personal and professional growth.
- Comprehensive health promotion, sustaining your health in the best possible way.
The minimum gross annual salary according to the collective bargaining agreement for this position is EUR 64,023.54 (full time). For the actual salary, the industry benchmark as well as your qualifications and experiences are taken into consideration.
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