Phd Thesis “the Blood-brain Barrier in Rare

vor 1 Woche

Wien, Österreich Austrian Institute of Technology Vollzeit

PhD Thesis “The blood-brain barrier in rare neurodevelopmental diseases”
- Center for Health & Bioresources
- You work on the role of the blood-brain barrier in rare neurodevelopmental diseases such as rasopathies
- You elucidate alterations in blood-brain barrier functionality based on mutations underlying the diseases.
- You investigate the role of the communication between brain endothelial cells and CNS cells such as astrocytes, pericytes and neurons for disease progression and therapeutic approaches.
- You combine high-throughput screening methods and cell culture models based on patient-derived human induced pluripotent stem cells (hiPSC) to evaluate the influence of mutations on the functionality of the blood-brain barrier.
- You implement novel methods to study the relevance of the cellular microenvironment on treatment strategies.
- You study drug transport (small molecules, nanoparticle carriers) under disease conditions.
- You support and supervise master’s students in the lab, write conference contributions and publish results in leading scientific journals
- You unravel changes at the blood-brain barrier in rare neurodevelopmental diseases and develop novel therapies using e.g., cutting edge hiPSC-based cell models and microscopic techniques.
- You are integrated in an interdisciplinary team evaluating in _vitro/in vivo _correlations.

Your qualifications as an
**Ingenious Partner**:

- MSc. in life sciences, e.g., molecular biology, molecular biosciences, molecular medicine, biotechnology, neurosciences, pharmaceutical sciences, or a related field
- Experimental skills in cell culture (preferentially endothelial, epithelial, hiPS cells, fibroblasts), protein chemistry and molecular biology
- Strong sense for responsibility and team spirit
- Excellent communication skills in English

**What to expect**:
EUR 2,464.80 gross per month for 30 hours/week based on the collective agreement. There will be additional company benefits. You will be part of our international AIT PhD community and participate in our AIT PhD framework programme. As a research institution, we are familiar with the supervision and execution of PhD theses, and we are looking forward to supporting you accordingly

**CV, cover letter** and
**certificates** online.

**For further information please contact**:

  • Phd Thesis “high-performance Computing for The

    vor 2 Wochen

    Wien, Österreich Austrian Institute of Technology Vollzeit

    PhD Thesis “High-performance computing for the analysis of future power systems” - Center for Energy - Currently there are around 160 international students participating in our **AIT PhD Programme**.This programme is carried out in cooperation with national or international universities and offers you the opportunity to conduct your dissertation in...

  • Phd Thesis “artificial Intelligence for

    vor 2 Wochen

    Wien, Österreich Austrian Institute of Technology Vollzeit

    We are Austria’s largest research and technology organisation and an international player in applied research for innovative infrastructure solutions. This makes us a powerful development partner for industry and a top employer in the scientific community. Our **Center for Energy** is seeking to hire new Ingenious Partners for our location in Vienna: PhD...

  • Phd Thesis “motion

    vor 2 Wochen

    Wien, Österreich Austrian Institute of Technology Vollzeit

    As **Austria's largest research and technology organisation** for applied research, we are dedicated to make substantial contributions to solving the major challenges of our time, climate change and digitisation. To achieve our goals, we rely on our specific research, development and technology competencies, which are the basis of our commitment to...

  • Phd Thesis “motion

    vor 2 Wochen

    Wien, Österreich Austrian Institute of Technology Vollzeit

    As **Austria's largest research and technology organisation** for applied research, we are dedicated to make substantial contributions to solving the major challenges of our time, climate change and digitisation. To achieve our goals, we rely on our specific research, development and technology competencies, which are the basis of our commitment to...

  • Phd Thesis “industrial Process Integration

    Vor 3 Tagen

    Wien, Österreich Austrian Institute of Technology Vollzeit

    PhD Thesis “Industrial process integration concepts for reversibly operated co-electrolysis for syngas production” - Center for Energy - In order to combat climate change and to optimally protect the environment, the energy system needs a safe and sustainable transformation. In this context, green hydrogen and its derivates (synthetic gases/ fuels) are...

  • Phd Thesis dna-based Data Storage in Vivo

    vor 2 Wochen

    Wien, Österreich Austrian Institute of Technology Vollzeit

    As **Austria's largest research and technology organisation** for applied research, we are dedicated to make substantial contributions to solving the major challenges of our time, climate change and digitalisation. To achieve our goals, we rely on our specific research, development and technology competencies, which are the basis of our commitment to...

  • Phd Thesis “solid Oxide Electrolysis Cells

    Vor 3 Tagen

    Wien, Österreich Austrian Institute of Technology Vollzeit

    PhD Thesis “Solid Oxide Electrolysis Cells (SOECs)” - Center for Energy - In order to combat climate change and to optimally protect the environment, the energy system needs a safe and sustainable transformation. In this context, green hydrogen and its derivates (synthetic gases/ fuels) are important energy carriers to decarbonize the energy...

  • Phd Thesis “enhanced Flexibility and Robustness

    vor 2 Wochen

    Wien, Österreich Austrian Institute of Technology Vollzeit

    PhD Thesis “Enhanced flexibility and robustness of autonomous systems through human - machine interaction” Cooperation with the TUFTS School of Engineering, Boston, USA - We are constantly looking for talented, innovative people, who want to develop "out-of-the-box" solutions for real-world problems. Now you have the opportunity to join our AIT-PhD...

  • Phd Thesis development and Characterization of Cathode Materials for Rechargeable Magnesium Batteries

    vor 2 Wochen

    Wien, Österreich Austrian Institute of Technology Vollzeit

    As **Austria's largest research and technology organisation** for applied research, we are dedicated to make substantial contributions to solving the major challenges of our time, climate change and digitalisation. To achieve our goals, we rely on our specific research, development and technology competencies, which are the basis of our commitment to...

  • Phd Thesis development and Characterization of Solid-state Polymer Battery Components

    vor 1 Tag

    Wien, Österreich Austrian Institute of Technology Vollzeit

    As **Austria's largest research and technology organisation** for applied research, we are dedicated to make substantial contributions to solving the major challenges of our time, climate change and digitalisation. To achieve our goals, we rely on our specific research, development and technology competencies, which are the basis of our commitment to...