(Senior) Lab Technician

Vor 7 Tagen

Wien, Österreich HOOKIPA Biotech GmbH Vollzeit

**About Hookipa**:
HOOKIPA Pharma Inc. (NASDAQ: HOOK) is a clinical-stage biopharmaceutical company focused on developing novel immunotherapies that mobilize and amplify targeted T cells to address unmet needs in cancer.

This leveraging its proprietary, versatile platform to engineer a broad pipeline of differentiated arenaviral therapeutics. These novel immunotherapies induce robust antigen-specific killer T cells to a broad range of self and non-self antigens, including viral antigens, tumor-associated antigens and neoantigens. HOOKIPA’s platform technology uses replicating viral vectors based on the target cancer, with the potential to induce killer T cell response levels previously not achieved by other immunotherapy approaches.

HOOKIPA’s pipeline includes wholly-owned investigational arenaviral immunotherapeutics targeting HPV16+ cancers, prostate cancer, KRAS-mutated cancers (including colorectal, pancreatic and lung), and other undisclosed projects. In addition, the company aims to develop functional cures of HBV and HIV in collaboration with Gilead.

**Position Summary**:
**Main Responsibilities**:

- Perform immunoassays (e.g., multicolor flow cytometry, ELISA, multiplex cytokine profiling)
- Perform _i_n vitro_ assays with human PBMCs and cell lines (e.g., transfection, ELISpot, cytotoxicity, proliferation, live cell imaging)
- Develop, optimize, and establish translational _in vitro_ and _ex vivo_ assays
- Execute, analyze, and present experiments in department meetings
- Cell culture of cell lines and primary cells (e.g., moDCs)
- Human tissue preparation and processing (e.g., PBMCs)
- Work with infectious materials under BSL-2 conditions
- Documentation of experiments according to internal guidelines
- Maintenance of laboratory equipment and material stocks
- Ability to work on weekends and statutory holidays if necessary

**Qualifications**:

- MTA, BTA, Dipl. Ing. (FH), B.Sc., M.Sc. or equivalent in relevant field (e.g., Biology, Immunology, Microbiology, Biotechnology)
- 1+ year of relevant hands-on lab experience (e.g., cell culture, immunoassays, BSL-2)
- Understanding of the concepts of immunology and immuno-oncology
- Experience with cell culture, flow cytometry, immunological assays and human PBMCs is a must
- Experience with molecular biology techniques (e.g., qPCR, transduction) is a plus
- Eager to acquire new knowledge, to learn, develop and optimize novel techniques
- Independent, efficient, proactive, well organized, solution
- and detail-oriented, hands-on mentality
- Motivated, flexible team player with the ability to handle multiple tasks in parallel and deliver high quality results under tight timelines
- MS Office and data analysis skills (GraphPad Prism, FlowJo)
- Strong interest in working in a creative environment and in participating in all aspects of preclinical development
- Excellent communication skills in English; German is a plus

**What we offer**:

- Strong international team with dedicated and passionate scientists and technicians
- State of the art infrastructure
- Excellent working atmosphere
- Opportunities for personal development
- Working in a multinational and multicultural environment
- Employee benefits such as health screening, public transportation card, Sodexo pass

We are required by Austrian law to post a minimum salary. The minimum monthly gross salary from EUR 2.754;
- (Lab Technician) to EUR 3.233;
- (Senior Lab Technician) based on fulltime (40 hours per week). Depending on experience and qualification salary can be negotiated. In addition, we offer a performance-related bonus payment and participation in our stock option compensation program.

Starting date: as soon as possible

**Contact**:

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