Master Thesis Positions

vor 3 Wochen


Wien, Österreich IMBA Institute of Molecular Biotechnology Vollzeit

**Master Student Position in Elling Lab**

**_The Elling Lab at IMBA Vienna is searching for a motivated Master student. _**
**_Our group is specialized on various modalities of genetic screening, foremost _**
**_CRISPR/Cas9 screens. The available project aims to contribute towards the _**
**_goal of establishing a new CRISPR/Cas9 screening paradigm for complex _**
**_systems such as in organoids and in vivo.
- **

CRISPR screening has revolutionized interrogation of
gene function in various assays. However, genome
wide screens at high resolution remain limited to
simple 2D cell culture models. _In vivo _as well as in
organoids representation bottlenecks are generated
by low infection efficiency, cell availability,

engraftment efficiency and differentiation bias that hinder high resolution genetic
screening. We have recently developed an IP-protected paradigm that empower
screening also in systems with these kinds of bottlenecks, foremost _in vivo_.
To empower genetic screening at high throughput we are also developing new
methods for the generation of transgenic cell lines.
molecular techniques. An early starting date is strongly preferred. Applications
highlighting relevant practical experience may be addressed to me directly via

Ulrich Elling



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