Phd Student

Vor 2 Tagen

Wien, Österreich St. Anna Kinderkrebsforschung Vollzeit

**Location**:
**Research group**:
**Working hours**:
Vienna

Sabine Taschner-Mandl Group

Full-time

To strengthen our excellent research team, which is focused on the development and research of innovative approaches for the treatment of childhood cancer, we are looking for a PhD Student (M/F/d) in the field of Cancer Molecular Biology. In this responsible role, you will have the unique opportunity to be part of a multidisciplinary competence center for pediatric oncology and to have a direct influence on the development of new cancer therapies.

The Taschner-Mandl group tackles unresolved questions of neuroblastoma pathogenesis and develops new diagnostic and therapeutic approaches to facilitate precision medicine for children with malignant tumors (e.g., Weiss T _et al._, _Nat Comm _2021, Rifatbegovic _et al., IJC_ 2018). In this project, we will study molecular drivers of tumorigenesis and progression in high-risk neuroblastoma. This project, will employ an array of state-of-the art technical approaches, including CRISPR/Cas9, primary tumor cell cultures and zebrafish models.

**As a PhD student, you will***:

- Join an exciting, multi-disciplinary environment with a strong support for your personal and professional development from your supervisor, team, and peers
- Be part of an interdisciplinary research project on deciphering the molecular drivers and mechanisms that underlie neuroblastoma pathogenesis
- Learn to take on ambitious research in close collaboration with experimental and clinical researchers
- You will contribute from the start, including planning of experiments and data acquisition
- You will provide thorough and creative thinking that makes these projects a success
- Monitor the literature and community resources to keep abreast latest developments and to identify information, data, and methods to integrate in your own work

**Your profile***:

- Laboratory experience, especially in cell culture and cellular assays, cloning, genome editing, biochemical assays preferred
- Motivation to pursue an ambitious research agenda
- Excellent verbal and written communication skills in English (German not required)
- Self-motivated, enthusiastic, and eager to learn
- Good team player, commitment, and creative
- Scientific mindset, problem solving attitude

**Our offer***:

- A meaningful, inspiring, and international environment
- An outstanding working atmosphere in a strong team with excellent research and development opportunities
- Access to state-of-the-art infrastructure
- Flexible working hours, home office possibilities, discounted lunch and other great benefits
- Great location in the center of Vienna, a capital of biomedical research in Europe with excellent quality of life

**Who we are***:
The St. Anna Children’s Cancer Research Institute (CCRI), located in the center of Vienna, the world’s most livable city and one of Europe’s most important places for biomedical research and life sciences, is an international and multidisciplinary competence center striving to improve treatment of children and adolescents with cancer by connecting translational and clinical research with open-minded exploration of basic disease mechanisms. Through close cooperation between clinic and research, the CCRI provides an ideal environment for cutting-edge research and its translation into clinical practice. To achieve our ultimate goal of advancing the well-being of patients, the CCRI constantly pushes scientific boundaries and strongly promotes close collaboration and exchange with external institutions like the Medical University of Vienna, CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, the Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA) and the Institute of Molecular Pathology (IMP).

The CCRI is an equal opportunity employer. We value diversity and are committed to providing a work environment of mutual respect to everyone without regard to ethnicity, religion, national origin, age, gender identity or expression, disability, or any other characteristic protected by applicable laws, regulations and ordinances.

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