Erc Postdoc Positions in Vascular, Computational, and Cardiac Biology

Vor 6 Tagen

Wien, Österreich IMBA – Institut für Molekulare Biotechnologie GmbH Vollzeit

The **Mendjan lab** aims to understand human heart development and disease through pioneering cardiac organoid technology (Hofbauer, Jahnel, Papai et al., 2021, _Cell_; Schmidt, Deyett, et al., 2023, _Cell_; Mendjan et al., 2025, _Nature Reviews_). Our main question is, how does the human heart grow? We hypothesize that key developmental processes, such as trabeculation, compaction, vascularization, and postnatal hypertrophy, must be recapitulated to ultimately generate a mature cardiac organoid model for studying heart disease and developing new therapies. We address these questions across biological scales from the subcellular to the organoid level, combining state-of-the-art imaging (electron, confocal, light sheet, two-photon microscopy), multi-omics (single cell/spatial transcriptomics/proteomics, phospho-proteomics, ATACseq, metabolomics), and whole organoid level analysis (morphometry, Ca2+ transients, voltage, contraction). To integrate our findings and generate new predictions and hypotheses, we aim to use multimodal deep learning and new systems analysis frameworks.
- **Research area**:

- The advertised positions entail working in small teams focused on:

- The establishment of a functional circulation in cardioids by using bioengineering and principles of cardiac coronary vasculogenesis to study cardiac diseases that have not been understood mechanistically in the human context.
- The development of computational tools to integrate cardioid multi-omics (e.g., scRNAseq) and imaging data analysis in collaboration with groups at the AITHYRA institute.
- The establishment of fetal heart-like proliferative growth conditions in cardioids as a proof of principle to study congenital chamber defects and human fetal heart regeneration.

** Your profile**:

- PhD and a strong publication record in vascular biology & bioengineering, computational biology, or cardiac/developmental biology and disease modeling.
- Extensive molecular, biochemical, cell, and tissue biology method skills.
- Experience in using computational analysis (biostatistics, machine learning, data science, physics, or a related field).

** Our offer**:

- A friendly, dynamic, and collaborative environment with state-of-the-art lab infrastructure, core lab funding, and Advanced ERC grant funding
- Extensive collaborative opportunities with other lab members, labs, and institutes
- High-performance life sciences and compute infrastructure with expert facility collaborators
- Opportunities to build outstanding leadership, computational, and experimental skills
- Freedom to develop independent research questions related to the research theme of the lab
- Close mentorship, training opportunities, and career development support
- Diverse social, cultural, and sports activities are organized by the campus and the city
- Excellent benefits, including insurance coverage and health services
- Gross salary of € 73.000 per year plus employers' pension/social benefits- Our lab is located in one of the leading research institutes and campuses worldwide: IMBA at the Vienna BioCenter (VBC) — see our lab page: Mendjan Lab at IMBA.
- Vienna is consistently among the top cities worldwide to live, with an outstanding cultural scene, reliable transportation, quick access to the region's stunning nature and parks, affordable housing and child care, free schools, and top higher education institutions.
- **How to apply?**:

  • ERC postdoc positions in vascular, computational, and cardiac biology

    Vor 5 Tagen

    Wien, W, Österreich IMBA – Institut für Molekulare Biotechnologie GmbH Vollzeit € 42.000 - € 60.000 pro Jahr

    The Mendjan lab aims to understand human heart development and disease through pioneering cardiac organoid technology (Hofbauer, Jahnel, Papai et al., 2021, Cell; Schmidt, Deyett, et al., 2023, Cell; Mendjan et al., 2025, Nature Reviews). Our main question is, how does the human heart grow? We hypothesize that key developmental processes, such as...

  • Cemm International Postdoc Program

    vor 2 Wochen

    Wien, Österreich CeMM Vollzeit

    What we offer: - A unique blend of a frontier research environment at top level with a strong medical and translational focus through the hospital setting and the connections to biotech and pharma. - An international group of highly collaborative colleagues that will help you achieve your scientific and career goals. - Top-notch environment with the ideas,...

  • Postdoc

    Vor 3 Tagen

    Wien, W, Österreich Max Perutz Labs Vienna Vollzeit € 40.000 - € 60.000 pro Jahr

    A postdoctoral position is available in the Martens Lab at the Max Perutz Labs, Vienna BioCenter.Our lab investigates the mechanisms of autophagy, a pathway that clears cells of harmful substances. For reasons that remain unclear, autophagy stalls at disease-associated protein aggregates, such as Alzheimer's Tau tangles. In this ERC-funded collaborative...

  • University Assistant Postdoc

    Vor 3 Tagen

    Wien, W, Österreich e-62a2-44c0-9487-4fa3a6a76166 Vollzeit € 40.000 - € 60.000 pro Jahr

    In recent years, Vienna has developed into one of the leading centers in evolutionary biology ). In addition to a stimulating scientific environment, Vienna also offers an extraordinarily high quality of life. Affordable housing, excellent public transport, great restaurants, a range of international schools, two operas, two music centers, many theaters, and...

  • Computational Biologist

    vor 2 Wochen

    Wien, Österreich Proxygen GmbH Vollzeit

    We are seeking a scientifically curious, technically strong, and self-driven **computational biologist** to join our team. In this role, you will work at the intersection of data science and biology - driving target discovery and biomarker identification efforts through independent exploration of proprietary and public datasets, statistical modeling, and...

  • Postdoc Research Group Siegert

    vor 1 Woche

    Wien, Österreich IST Austria Vollzeit

    Klosterneuburg (Vienna), Austria € 57,680 gross/year **Application Deadline**: flexible start date Postdoctoral position Postdoc with focus on applied data analysis in Research Group Siegert. In recent years, microglia, traditionally classified as immune-response, have been shown to adjust synaptic connection during development and disease. However,...

  • Phd Position in Physical

    vor 2 Wochen

    Wien, Österreich Christian Doppler Labor für SDS Institut für Mikroelektronik, TU Wien Vollzeit

    **Research Topic**: Exploration of reliability phenomena in modern transistor technologies **About us**: The Institute for Microelectronics is a globally recognized research institute in micro - and nano-electronics. We cover all aspects of analyzing and investigating microelectronic devices experimentally and theoretically. This includes studying the...

  • Discovery Scientist in Immunology

    Vor 4 Tagen

    Wien, Österreich Solgate GmbH Vollzeit

    Discovery Scientist in Immunology (Postdoc level) Solgate is a new research-driven biopharmaceutical startup that develops drugs targeting solute carrier (SLC) proteins, the largest family of membrane transporters. By modulating the function of the “gates” to cellular metabolism, Solgate aims to address unmet medical needs in neurological diseases, in...

  • Scientist - nucleic Acid Chemistry

    vor 2 Wochen

    Wien, Österreich Ribbon Biolabs Vollzeit

    Ribbon Biolabs is a young biotech company with locations in Vienna and in Klosterneuburg (outskirts of Vienna) developing the next technological wave of error-proof DNA synthesis. With our approach, we are developing a cost-efficient platform to produce long and complex DNA molecules, thereby enabling a new generation of biopharmaceutical processes and other...

  • Bioinformatician in Development and Disease

    vor 2 Wochen

    Wien, Österreich Research Institute of Molecular Pathology Vollzeit

    The ERC-funded Pauli and Obenauf Groups at the Research Institute of Molecular Pathology (IMP) in Vienna, Austria, are jointly recruiting a highly motivated **bioinformatician with interest in biology**. He/she will work on research projects that focus on elucidating molecular mechanisms in development and cancer biology. **Bioinformatician in Development...