Exciting PhD Opportunity: Analytical Methods for Vaccine–Antigen Interactions

School of Chemical and Biomedical Engineering - School of Computing and Information Systems Organisation/Company The University of Melbourne Department School of Chemical and Biomedical Engineering - School of Computing and Information Systems Research Field Engineering » Chemical engineering Chemistry » Biochemistry Chemistry » Analytical chemistry Researcher Profile First Stage Researcher (R1) Positions PhD Positions Country Australia Application Deadline 26 Jan 2026 - 23:59 (Australia/Melbourne) Type of Contract Not Applicable Job Status Full-time Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No Offer Description Exciting PhD Opportunity: Analytical Methods for Vaccine–Antigen Interactions Institution: University of Melbourne in partnership with Zoetis Location: Bio21 Institute, University of Melbourne & Zoetis Parkville Site Duration: 3–4 years (standard PhD) Project Overview We are seeking an enthusiastic and motivated PhD candidate to develop innovative, animal-free analytical methods for detecting interactions between Zoetis clostridial vaccines and their target antigens. Current rabbit-based testing methods have significant limitations. This project will establish a quantitatively accurate, non-animal alternative that meets regulatory and ethical standards whilst maintaining scientific rigour. You will first survey the literature for alternative analytical approaches for vaccine–antigen quantification. You will then learn current industry best practice methods involving ELISA assays and biosensor technology at Zoetis before developing and evaluating new quantitative mass spectrometry methods. Using a broad range of industry vaccine and antigen samples (not live bacteria or toxins) you will assess the specificity and selectivity, as well as the sensitivity, precision and accuracy of both established and new methods. You will work with local and international Zoetis team members, as well as researchers from the Bio21 Institute, including the Mass Spectrometry platform. The PhD will potentially involve a visit to an international Zoetis site. Candidate Profile We are looking for candidates with: Bachelor's degree (Honours) or Master's degree in Chemistry, Biochemistry, Pharmaceutical Sciences, Analytical Chemistry, Chemical Engineering or related discipline. Strong laboratory skills and attention to experimental detail. Experience with analytical techniques (ELISA, mass spectrometry, or immunoassays preferred). Excellent written and verbal communication skills. Ability to work collaboratively in both academic and industry environments. Problem-solving mindset and adaptability to evolving project directions. What We Offer Dual Supervision: Expert guidance from University of Melbourne and Zoetis scientists. Flexible Working Arrangements: Split time between Bio21 and Zoetis Parkville site, tailored to experimental needs. Access to World-Class Facilities: Bio21 Mass Spectrometry facility and Zoetis analytical laboratories. Industry Experience: Valuable exposure to pharmaceutical development and regulatory considerations and experience working with local and international Zoetis team members. Competitive Stipend. How to Apply Academic transcripts Statement of interest (500 words maximum) outlining your motivation and relevant experience Contact details for two academic referees Application Deadline: 26 January 2026 Both international and local students considered. Candidates already located in Australia preferred. #J-18808-Ljbffr