Paid Diploma

vor 2 Monaten

Graz, Österreich Research Center Pharmaceutical Engineering GmbH Vollzeit

Paid Diploma / Master's Thesis
**Influence of material properties on the mixing behavior in the feed frame of a industrial scale tablet press**
Ref.No DA179

To dedicated students of Chemical Engineering, Pharmaceutical Engineering, Pharmacy or related studies.

**Objective**

Nowadays, a common method for the continuous production of tablets is the direct compaction (DC). In such a DC line, the feed frame acts as the last station previous to the actual tableting process and is responsible for evenly distributing the active pharmaceutical ingredient (API) and excipients, and continuously delivering it to the matrices. However, the material properties of APIs and excipients can influcence the mixing behaviour in the feed frame.

In the course of this diploma / master´s thesis the impact of the material properties on the mixing behaviour in the feed frame of a tablet press in industrial scale size was investigated. Therefore, particle size, shape, density, and surface characteristics of differents APIs and excipients will be analyzed and compared in terms of their mixing performance.

**Withing the framework of this diploma / master’s thesis we offer the following**:

- Extensive participation in a top-level and industrially relevant research project in an international environment
- Supervised training in the task
- Assistance of experienced staff with the implementation of innovative ideas
- Access to highly modern infrastructure on campus of Graz University of Technology
- Assistance with the publication of results

**Financing**
- Compensation on the basis of a service contract

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