Laboratory Technician: Epigenetics, Cell Therapy

vor 6 Monaten


Wien, Österreich CeMM Vollzeit

We are recruiting a _research technician_ who wants to contribute to cutting-edge biomedical research in a highly ambitious, collaborative, and international environment. Our lab is based at the _CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences in Vienna_, on the campus of one of the world’s largest hospitals._

Relevant qualifications
- Bachelor’s or master’s degree (or equivalent) with strong wet-lab experience and keen interest in working as a research technician
- High accuracy, reliability, precision under time pressure, and organizational skills
- Prior experience working with molecular biology techniques including cell culture and DNA/RNA assays
- Friendly, collaborative mindset and ability to work well in an international environment
- Written and oral communication skills in English (German language skills are not required)
- Proactive mindset, getting-things-done attitude, and motivation to work hard and do well in a fast-moving area of biomedicine
- We are open to applicants who want to gain practical experience prior to a PhD (former technicians have moved on to PhDs at top places including IRB Barcelona, DKFZ Heidelberg, CRUK Manchester) but we require a 3-years’ time commitment to make it productive

Typical tasks
- High-throughput profiling of patient samples, including next generation sequencing, single-cell technologies, and CRISPR screens
- Cell culture and cell-based assays including the cultivation of patient-derived organoids, immune cells, and CAR T cell therapies
- Optimization and testing of new assays and protocols, for example for cancer epigenetics, tumor immunology, and stem cell biology
- Contribution to lab management, training of new lab members, and scientific publications

We seek to advance biomedicine with technology-driven research, combining functional genomics, bioinformatics, and machine learning with a focus on understanding epigenetic cell states and contributing to cancer and immunity. We are internationally well-connected and strongly committed to the career development of all group members. PhD students and postdocs in our research group have won prestigious fellowships and prizes; three out of three PhD students and five out of six postdocs who graduated from our group have already obtained principal investigator positions and started their own research groups at universities / research institutes in Austria and abroad. Main areas of research include:

- _Computational biology_. Bioinformatic methods are essential for data-driven biomedical research. We develop algorithms and software for large-scale data analysis, and we pursue clinical collaborations to establish medical impact.
- _Single-cell genomics_. Many diseases involve deregulated epigenetic cell states. As members of the Human Cell Atlas, we use single-cell sequencing and organoids to dissect the gene-regulatory foundations of cancer and immunity.
- Machine learning. Huge datasets pose new analytical challenges. As members of the European Laboratory for Learning and Intelligent Systems, we develop methods for interpretable deep learning and artificial intelligence in biology.
- Immune cell engineering. CAR T cells have shown dramatic efficacy for blood cancers and may spearhead a broader shift toward personalized, cell-based therapies. We use high-throughput technology to design synthetic immune cells.

The Principal Investigator

About the Institute

We offer
- Work within an experienced, interdisciplinary, and international team at one of Austria’s leading research institutes
- Ample opportunities to contribute and gain experience in a key area of biomedical research and precision medicine
- An inspiring workplace with an international setting, strong team spirit, and an excellent work climate
- A wide range of social, cultural, and sports activities organized by the institute
- Excellent employee benefits including full insurance coverage (health, accident, retirement), health care services, subsidized cafeteria
- Monthly gross salary of from EUR 2.850,00 to EUR 3.500,00 paid out 14 times yearly (following the recommendations of FWF).
- Support for relocating to Vienna is provided (relocation reimbursement, visa support, etc.)



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