(Senior) Scientist

vor 1 Monat

Wien, Österreich Hookipa Pharma Vollzeit

Date: Aug 18, 2023- Location: Wien, AT**About HOOKIPA**:
HOOKIPA Pharma Inc. (NASDAQ: HOOK) is a clinical-stage biopharmaceutical company focused on developing novel immunotherapies, based on its proprietary arenavirus platform, which are designed to mobilize and amplify targeted T cells and thereby fight or prevent serious disease. HOOKIPA’s replicating and non-replicating technologies are engineered to induce robust and durable antigen-specific CD8+ cell responses and pathogen-neutralizing antibodies. HOOKIPA’s pipeline includes its wholly owned investigational arenaviral immunotherapies targeting HPV16+ cancers, prostate cancer, KRAS-mutated cancers (including colorectal, pancreatic and lung), and other undisclosed programs. In addition, HOOKIPA aims to develop functional cures for HBV and HIV in collaboration with Gilead.

**About HOOKIPA**:
HOOKIPA Pharma Inc. (NASDAQ: HOOK) is a clinical-stage biopharmaceutical company focused on developing novel immunotherapies, based on its proprietary arenavirus platform, which are designed to mobilize and amplify targeted T cells and thereby fight or prevent serious disease. HOOKIPA’s replicating and non-replicating technologies are engineered to induce robust and durable antigen-specific CD8+ cell responses and pathogen-neutralizing antibodies. HOOKIPA’s pipeline includes its wholly owned investigational arenaviral immunotherapies targeting HPV16+ cancers, prostate cancer, KRAS-mutated cancers (including colorectal, pancreatic and lung), and other undisclosed programs. In addition, HOOKIPA aims to develop functional cures for HBV and HIV in collaboration with Gilead.

**Position Summary**:
We are looking for an enthusiastic and committed (senior) scientist to lead a translational research team aiming to characterize the immunological response to arenavirus immunotherapy in human in vitro models and clinical trial samples.

**Main Responsibilities**:

- Lead translational research projects with a team of 3 experienced lab technicians.
- Develop scientific strategy for translational research projects, in close consultation with the head of department and relevant stakeholders (Clinical Biomarkers, Global R&D )
- Design and perform experiments focused on antigen specific CD8+ T cell characterization in primary human cells (e.g. ELISpot, FACS, gene expression analyzes, TCR sequencing )
- Analyze and interpret data, troubleshoot as required.
- Implement these techniques for exploratory analyses of clinical trial samples, according to GCP guidelines.
- Write, review and approve SOPs, study plans and reports.
- Oversee technical and theoretical training of team members.
- Evaluate deviations, review, approve and release data.
- Present and discuss results at internal and external meetings.
- Manage team´s resources and timelines, coordinating the work of team members and external partners and prioritizing projects and tasks as needed.
- Maintain engagement of team members and promote their personal development.
- Contribute to a friendly and productive work environment, consistently thriving for improvement.

**Qualifications & Skills**:

- PhD in life sciences
- Minimum 3 years hands-on laboratory experience with immunological assays and primary human cell culture techniques
- Experience with working under GCP guidelines for clinical trial sample analysis is an advantage.
- Independent and proactive work style, detail-oriented, well-organized
- Strong interpersonal skills, open-minded and flexible team-player
- Able to motivate others and lead by example
- Excellent written and oral communication skills in English

**What we offer**:

- Strong team with dedicated and passionate employees
- State of the art infrastructure
- An excellent working atmosphere
- Opportunities for personal development
- Employee benefits such as health screening, public transportation card, Sodexo pass
- Working in a multinational and multicultural environment

We are required by Austrian law to post a minimum salary. The minimum monthly gross salary for this position is EUR 4.112;
- based on fulltime (40 hours per week); depending on experience and qualification salary can be negotiated. In addition, we offer a performance-related bonus payment and participation in our stock option compensation program. The position is a **temporary **replacement (Karenzvertretung) and is expected to last until 30.06.2025.

Starting date: as soon as possible

**Contact**:
If you (M/F/d) are interested in this challenging position, please send your CV including a cover letter (summarizing your qualification and experiences) together with your credentials.

**Contact**:
**Contact**:

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