Scientist Upstream Process Development
Vor 2 Tagen
**Location**:Rinnböckstrasse 3, close to Vienna Biocenter, St. Marx, 1030 Vienna
**Start date**:From 05.01.2026 onwards
**Job Type**:Full-time (40 hours)
**Company description**: Valanx Biotech is reimagining the future of protein-based therapeutics through next-generation bioconjugation. Our proprietary synthetic biology platform expands and optimizes design opportunities of biologics — unlocking a new era of safer, more effective, and customizable medicines. At Valanx, innovation meets precision. We’re a team of scientists, engineers, and entrepreneurs passionate about transforming how biologics are made and delivered.
- Design and conduct hands-on experimental work in upstream process development (cell culture and stable cell line generation, antibody production) for antibody drug conjugate development
- Develop and optimize process parameters to improve yield, quality, and consistency of antibodies with guidance
- Troubleshoot upstream bioprocessing challenges, improving process robustness for tech transfer to CDMOs & GMP readiness
- Contribute to the development of product characterization assays (e.g., cell-functional assays).
- Draft and review technical reports, regulatory support documents and CMC regulatory submissions.
- Maintain accurate and complete records, ensuring compliance with documentation management systems.
**Preferred Qualifications**:
- MSc. / Dipl.Ing./ PhD in Biotechnology, Biochemistry, Molecular Biology or related field.
- Deep knowledge and hands-on experience in mammalian cell culture and recombinant protein expression systems (CHO and/or HEK-293) under aseptic conditions
- Experienced in transient expression, stable cell line generation and characterization, flow cytometry and cell sorting.
- Practical experience in recombinant DNA technology, RT-qPCR and cloning as well in establishing and/or performing ELISA-based assays and cell-functional assays.
- Ability to establish new methods and assays in a self-reliant manner.
- A passion to work hands-on in the lab.
- to mid-sized biotech industry, specifically in upstream process development, with hands-on experience in stable cell line generation and antibody production
- Adaptable and resilient in rapidly changing start-up settings, with a balance of teamwork and self-driven initiative.
- Strong interpersonal, verbal, and written communication skills (English)
- Good IT skills (MS Office, Electronic Lab Notebook).
**We offer**:
- Work on the cutting edge of Science in Synthetic Biology within Antibody-drug conjugate development
- Strong team with dedicated and passionate scientists
- Flexible working time
- Compensation for Wiener Linien yearly ticket
- An excellent and creative work environment where your ideas are welcomed
- Opportunities for personal development
We are obligated by law to state a minimum salary of 3063,55 EUR gross monthly in agreement with the collective contracts but are offering overcompensation according to industry standards.
To apply, please submit your resume to the form on our website
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