Paid Diploma

vor 6 Monaten

Graz, Österreich Research Center Pharmaceutical Engineering GmbH Vollzeit

Paid Diploma / Master's Thesis

**Optimization of a continuous manufacturing line for potent APIs**
Ref.No DA167

To dedicated students of CHEMISTRY, CHEMICAL ENGINEERING, and PROCESS ENGINEERING who want to participate in an industry-related project.Objective

**Objective**

Among experts, the continuous manufacturing of APIs (Active Pharmaceutical Ingredients) is considered the next big leap in the pharmaceutical industry. Therefore, implementing an automated, continuous manufacturing line is one of the most exciting and challenging chemical engineering endeavors. A flawlessly-working, transition-free setup can be achieved by optimizing each unit operation regarding its subsequentially installed counterparts.

In this setup, an organometallic reaction, carried out in flow, is followed by a counter-current operated extraction unit utilizing membrane separators. On-line colorimetric detection of the pollutant validates the functionality of the extraction unit.
Tasks

**Tasks**
- Literature research on continuous manufacturing and organometallic reactions
- Optimize the working principle of each unit operation on an already existing framework
- Control and automate lab equipment via the python serial module
- Assist experienced staff & work independently by contributing your innovative idea

**Withing the framework of this diploma / master’s thesis we offer the following**:

- Participation in a top-level and industrially relevant research project
- Possibility of getting a second authorship in a scientific paper
- Access to highly modern infrastructure on the campus of Graz University of Technology

**Financing**
- Compensation on the basis of a service contract

If you are interested in writing your thesis at the interface between university research and industry/ business and to contribute to the optimization of product and process development in the pharmaceutical industry, please contact us indicating the reference number.

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