Paid Diploma

Vor 4 Tagen

Graz, Österreich Research Center Pharmaceutical Engineering GmbH Vollzeit

Paid Diploma / Master's Thesis
**Co-Processing of API combinations for Inhalation therapy**
Ref.No DA180

To dedicated students of Pharmacy, Chemistry, Pharmaceutical Engineering or related disciplines.

**Objective**

Within this project we will develop novel, co-processed drug particles for the treatment of lung diseases. The co-processing systems to be investigated are co-crystals or co-amorphous systems.

Screening methods will include thermal techniques such as hot scanning microscopy (HSM), vacuum compression molding and co milling in conjunction with differential scanning calorimetry (DSC). Promising active ingredient combinations will be selected for laboratory-scale batch production trials via spray drying.

Another part of this work will be dedicated to full characterization of the produced batches in terms of morphology and physico-chemical characterization.

Further, the powders will be tested regarding their suitability for dry-powder-inhalation, using an impactor device to assess their aerodynamic performance.

**Withing the framework of this diploma / master’s thesis we offer the following**:

- Extensive participation in a top-level and industrially relevant research project in an international environment
- Supervised training in the task
- Assistance of experienced staff with the implementation of innovative ideas
- Access to highly modern infrastructure on campus of Graz University of Technology
- Assistance with the publication of results

**Financing**:

- Compensation on the basis of a service contract

If you are interested in writing your thesis at the interface between university research and industry/ business and to contribute to the optimization of product and process development in the pharmaceutical industry, please contact us indicating the reference number.

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