Master Student Position

vor 1 Woche

Wien, Österreich Max F. Perutz Laboratories Vollzeit

**About the research project**:
Tight control of RNA processing and degradation is a crucial step of post-transcriptional gene regulation. The RNA exosome is a big multisubunit complex, that regulates nearly every category of transcripts, synthesized in the cell. While the recruitment of the exosome to its substrates and structural basis for it are well described, the contribution of individual subunits to the exosome function and assembly remains elusive. The advertised project utilizes various protein perturbation techniques (**inducible KO, AID-system**) combined with** flow-cytometry, microscopy** and **classical biochemistry** to gain in-depth insights into RNA exosome biology. The project offers the opportunity to acquire a broad range of technical skills and to learn to independently conduct a research project.

**Application**:

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