Research Technician: Epigenetics, Cell Therapy

vor 1 Woche


Wien, Österreich CeMM Vollzeit

We are recruiting a research technician who wants to contribute to cutting-edge biomedical research in a highly ambitious, collaborative, and international environment. Our lab is based at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences in Vienna, on the campus of one of the world’s largest hospitals.

Your Profile
- Bachelor’s or master’s degree (or equivalent) with strong wet-lab experience and keen interest in working as a research technician
- High accuracy, reliability, precision under time pressure, and organizational skills
- Prior experience working with molecular biology techniques including cell culture and DNA/RNA assays
- Friendly, collaborative mindset and ability to work well in an international environment
- Written and oral communication skills in English (German language skills are not required)
- Proactive mindset, getting-things-done attitude, and motivation to work hard and do well in a fast-moving area of biomedicine
- We are open to applicants who want to gain practical experience prior to a PhD (former technicians have moved on to PhDs at top places including IRB Barcelona, DKFZ Heidelberg, CRUK Manchester) but we require a 3-years’ time commitment to make it productive

Your Tasks
- High-throughput profiling of patient samples, including next generation sequencing, single-cell technologies, and CRISPR screens
- Cell culture and cell-based assays including the cultivation of patient-derived organoids, immune cells, and CAR T cell therapies
- Optimization and testing of new assays and protocols, for example for cancer epigenetics, tumor immunology, and stem cell biology
- Contribution to lab management, training of new lab members, and scientific publications

The Medical Epigenomics Lab at CeMM seeks to advance precision medicine through collaborative, technology-driven biomedical research, developing wet-lab and computational methods and investigating the epigenetic (de)regulation underlying cancer and immunity.
- _Single-cell genomics_. Many diseases show deregulation of epigenetic cell states. As members of the Human Cell Atlas, we use single-cell sequencing and human organoids to dissect the gene-regulatory foundations of cancer & immunity.
- _Computational biology_. Bioinformatic methods are essential for advancing biomedical research. We develop algorithms and software for large-scale data analysis, and we pursue clinical collaborations to demonstrate health impact.
- _High-throughput technology_. Many groundbreaking discoveries are driven by new technologies. We invest heavily into technology development, including single-cell sequencing, CRISPR screens, epigenome editing, and synthetic biology.
- _Machine learning_. Huge datasets pose new analytical challenges. As members of the European Laboratory for Learning and Intelligent Systems, we develop methods for interpretable deep learning and artificial intelligence in biology.
- _Immune cell engineering_. CAR T cells have shown dramatic efficacy for blood cancers and may spearhead a broad shift toward personalized, cell-based therapies. We use high-throughput technology to design synthetic immune cells.

The mission of CeMM is to achieve maximum scientific innovation in molecular medicine to improve healthcare. At CeMM, an international and creative team of scientists and medical doctors pursues free-minded basic life science research in a large and vibrant hospital environment characterized by outstanding medical tradition and practice.

CeMM’s research is based on post-genomic technologies and focuses on societally important diseases, such as immune disorders and infections, cancer and metabolic disorders. An additional focus lies on aging research_._ CeMM operates in a unique mode of supercooperation, connecting biology with medicine, experiments with computation, discovery with translation, and science with society and the arts. CeMM trains a modern blend of biomedical scientists to make great contributions. The goal of CeMM is to pioneer the science that nurtures the precise, personalized, predictive, and preventive medicine of the future.

CeMM trains a modern blend of biomedical scientists and is located at the campus of the General Hospital and the Medical University of Vienna. More than 150 people from 49 nationalities are working at CeMM. CeMM promotes equal opportunity and harbors a mix of different talents, backgrounds, competences, and interests.

We offer
- Work within an experienced, interdisciplinary, and international team at one of Austria’s leading research institutes
- Ample opportunities to contribute and gain experience in a key area of biomedical research and precision medicine
- An inspiring workplace with an international setting, strong team spirit, and an excellent work climate
- A wide range of social, cultural, and sports activities organized by the institute
- Excellent employee benefits including full insurance coverage (health, accident, retirement),



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